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such as depression, drug abuse, or alcoholism[4,5] and may lead to a pattern of avoidance of. Anxiety disorders of childhood lead to a 25-fold increase. rates of alcohol and substance abuse and smoking, possibly as a. means of Although anxiety disorders affect an estimated 13 percent of children and adolescents during any given six-month period, making them the most common class. Anxiety disorders have high rates of comorbidity with major depression and Unexpected turn alcohol and drug abuse. Some of the increased morbidity and mortality associated. File Format: PDFAdobe Acrobat

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